PARIS  Mousa Dembele Jersey , May 12 (Xinhua) -- Ligue 1 club Monaco announced Tuesday that head coach Leonardo Jardim has extended his contract with the top-flight soccer league's runners-up until 30 June 2019.

The 40-year-old Portuguese was appointed to the post last summer on a two-year deal after leaving Sporting Lisbon.

"Since arriving in the Principality, the Portuguese coach has demonstrated the quality of his work, his efficiency and his ambition to develop the club's project," read a statement on the club's website.

"By securing Leonardo Jardim's services as coach until 2019, AS Monaco is demonstrating its commitment to stability  Michel Vorm Jersey , focusing on continued progress and achieving its ambitions for the future," it added.

Monaco sit now on the third in Ligue 1 standings with just two rounds left in the 2014-2015 campaign, trailing 12 points to the leaders and holders Paris Saint-Germain and 6 points behind second- placed Lyon.

"It is a sign of confidence from the club, the board, to sign this extension  Lucas Moura Jersey ," Jardim told the website. "We have worked hard this season to put in place a new project and I am convinced that the best is to come."

"There are a lot of quality youngsters in this team, we need to build on what we have shown this season. The club is ambitious and so am I," he added.

"It is an important step for our club because we wish to build over the long-term with Leonardo Jardim," said Monaco vice- president Vadim Vasilyev. "With his staff, he has done a remarkable job this season  Kyle Walker-Peters Jersey , obtaining very good results in Ligue 1 and in the Champions League."

Monaco came out the surprising quarterfinalists of the UEFA Champions League by ousting English Premierships' Arsenal but lost 1-0 on aggregate to Juventus in last eight matchups.

SAN FRANCISCO, Jan. 27 (Xinhua) -- French scientists have found that people's biological clock can be a vital factor in fighting inflammatory disease such as fulminant hepatitis, a new study suggests.

Scientists from the National Institute of Health and Medical Research (Inserm), Pasteur Institute of Lille and University of Lille in northern France have worked on the links between biological clock and inflammatory disease.

Through experiments on human cells and mice, they discovered that the anti-inflammatory action of a biological clock protein could block the onset of fulminant hepatitis by easing symptoms and increasing survival rates.

The findings of their study were carried in the latest edition of Gastroenterology.

Fulminant hepatitis is a serious disease that has no effective cure  Kieran Trippier Jersey , except liver transplant within 24 hours after the onset of its symptoms.

The illness can cause rapid deterioration of tissue ad liver function in patients, in addition to blood coagulation disorders and irreparable brain damage.

The French scientists found a biological clock protein called Rev-erba, which notably targets adipose tissue, together with liver, skeletal muscle and brain cells.

Their experiments on human immune system cells and on mice established the fact that inflammation follows a circadian rhythm.

Test results of mice  Juan Foyth Jersey , which received Rev-erba-activating treatment, showed less severe forms of the disease and a higher survival rate.

The French researchers observed the same effect in vitro on human cells, which increased their confidence of developing a new treatment for acute fulminant hepatitis.

"This offers new hopes for researchers, notably in terms of potential improvements in quality of life and longevity among patients suffering from chronic inflammatory disease," said Inserm researcher Helene Duez.

"The Miseducation of Cameron Post  Josh Onomah Jersey ," a powerful drama about the real-life controversial practice of gay conversion therapy, came away with the top prize as the Sundance Film Festival wrapped Saturday.

Starring Chloe Grace Moretz, it delighted and shocked audiences at its world premiere in the Utah mountains with its story of a teenage girl forced into therapy after being caught having a sexual encounter with the prom queen.

"On behalf of the entire 'Cameron Post' team we want to dedicate this to the LGBTQ survivors of sexual conversion therapy," said Moretz.

"We just wanted to make this movie to shine a light onto the fact that it is only illegal in nine states out of the 50 states in this country to practice sexual conversion therapy."

Its director Desiree Akhavan had pre-recorded an acceptance speech for the grand jury prize in Sundance's "US dramatic competition" section but it could not be played on a night beset by technical difficulties.

"Kailash," about one man's crusade to end child slavery  Jan Vertonghen Jersey , won best US documentary while the US dramatic audience award - the second prize to the grand jury award - went to Andrew Heckler's "Burden."

Chinese dark comedy "Dead Pigs," directed by Chinese director Cathy Yan, won the Special Jury Award for an Ensemble cast at Sundance.

The US documentary directing prize went to Alexandria Bombach for "On Her Shoulders," - a portrait of a Yazidi girl who survived sexual slavery at the hands of the Islamic State group - while the US documentary audience award went to "The Sentence."

"Butterflies" came away with the grand jury prize for world drama while "Of Fathers and Sons," a study of jihadi radicalization in the home  Hugo Lloris Jersey , from celebrated Syrian filmmaker Talal Derki, won the world cinema documentary competition.

The Sundance Film Festival, founded by actor Robert Redford, is considered a showcase for independent and documentary films, and festival winners often go on to receive critical acclaim and Hollywood awards season glory.

Among the titles from the 2017 edition of the festival picking up trophies at Hollywood's various ceremonies are Jordan Peele's "Get Out  Harry Winks Jersey ," which played out of competition as a midnight screening.

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