TENNESSEE (8-5) at SAN FRANCISCO (3-10)

Sunday Cheap Rashaan Gaulden Jersey , 4:25 p.m. ET, CBS

OPENING LINE – Titans by 2 1/2

RECORD VS. SPREAD – Tennessee 5-7-1, San Francisco 7-6

SERIES RECORD – 49ers lead 8-5

LAST MEETING – 49ers beat Titans 31-17, Oct. 20 Bills Phillip Gaines Jersey , 2013

LAST WEEK – Titans lost to Cardinals 12-7; 49ers beat Texans 26-16

AP PRO32 RANKING – Titans No. 13, 49ers No. 26 (tie)

TITANS OFFENSE – OVERALL (21), RUSH (10), PASS (27).

TITANS DEFENSE – OVERALL (9) Cheap Orlando Brown Jr. Jersey , RUSH (5), PASS (22).

49ERS OFFENSE – OVERALL (17), RUSH (22), PASS (16).

49ERS DEFENSE – OVERALL (25) Buccaneers Vita Vea Jersey , RUSH (25), PASS (20).

STREAKS, STATS AND NOTES – Titans spent week in Arizona following game at Cardinals to reduce travel. … Titans making first visit to Levi's Stadium. Second straight game Titans have played in a stadium for first time, following University of Phoenix Stadium. … Titans one win from posting first back-to-back winning seasons since 2007-08. … Tennessee QB Marcus Mariota has thrown eight INTs past four games to give him career-worst 14 on season. … Mariota has had four of his eight career game-winning drives this season. … Tennessee made eight sacks twice in past three games after having not done it since 1985. … Titans have 20 sacks in three games Cheap Duron Harmon Jersey , most by NFL team over any three-game span this season and most for franchise in three-game span during Titans' era since 1999. … Tennessee held seven straight teams to fewer than 100 yards rushing before allowing 136 last week. … Niners seek first three-game winning streak since 2014. … QB Jimmy Garoppolo makes first home start for San Francisco. His 627 yards passing past two weeks are most for any 49ers QB in first two starts with team since merger. … Garoppolo one of four active QBs to win first four career starts. … San Francisco rookie LB Reuben Foster has 45 tackles in past five games. … 49ers third worst in NFL with TDs on 41.7 percent of red zone trips. … San Francisco FB Kyle Juszczyk had career-high 64 yards receiving last week. … 49ers K Robbie Gould made 14 straight FGs. … Fantasy Tip: San Francisco WR Marquise Goodwin has developed into Garoppolo's favorite target with 14 catches for 205 yards in two games together.

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